product

Allopregnanolone Pregnanalone CAS:516-54-1

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Product Tags

Allopregnanolone (ALLO), also known as 3α-hydroxy-5α-pregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of gamma-amininobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant activity.
Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).

Basic Info

Chemical Name

3α-hydroxy-5α-pregnan-20-one

Synonyms

(3α)-Allopregnanolone;Pregnan-20-one, 3-hydroxy-, (3α,5α)-;ALLOPREGNAN-3ALPHA-OL-20-ONE;3alpha-hydroxy-5alpha-pregnan-20-one;

CAS No.

516-54-1

Molecular Formula

C21H34O2

Molecular Weight

318.49300

PSA

37.30000

LogP

4.59520

 

Numbering system

UNII

S39XZ5QV8Y

Properties

Density

1.053g/cm3

Boiling Point

431.2ºC at 760mmHg

Flash Point

183.9ºC

Refractive Index

1.524

Storage Condition

Store at RT

Safety Info

Safety Statements

S22; S24/25

 

 

Company Introduction 

Wuhan Bosman Medicine Technology Co., Ltd. is a technological company with independent intellectual property rights, engaged in the development, production and operation of chemical products. Our company is a comprehensive enterprise integrating scientific and technological development and mass production. It is a factory specializing in the research and development and production of methylamine hydrochloride series products. The product quality is domestically leading. At the same time, we continue to explore and develop with the joint efforts of all employees of the company. The company has achieved rapid development, and its products are sold all over the world and are well received by customers. Our company has been responding to the call of the local government to speed up the adjustment of industrial structure and gradually expand production capacity. Currently, there are more than 600 employees in the factory and 29 technicians; among them, 11 are masters, 4 are PhDs, and 3 are MBAs. The annual planned production capacity of monomethylamine hydrochloride is more than 900 tons, the planned annual production capacity of dimethylamine hydrochloride is more than 500 tons, and the annual planned production capacity of trimethylamine hydrochloride is more than 700 tons. Products are exported to Southeast Asia, Europe, North America and South America. Our company's product quality is stable and reliable, and it has established friendly and stable business relationships with many well-known domestic and foreign companies. Our unit adheres to the principle of honest management, adheres to the tenet of quality assurance, and customer first, provides customers with products of outstanding quality and stable performance, and has won the unanimous recognition and favor of customers with efficient and perfect after-sales service. We look forward to working with colleagues and friends from all walks of life to create a new future.

 

Packaging  Details 

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2-phenylacetamide

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2-Dimethylaminoisopropyl Chloride

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4-oxopiperidinium chloride

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4-methylpropiophenone

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Phenyl-2-nitropropene

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4-Fluorophenylacetone

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4-Amino-3,5-dichlorophenacylbromide

37148-47-3

2-Bromo-1-phenyl-1-pentanone

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4-Amino-3,5-dichloroacetophenone

37148-48-4

Ethyl 2-Bromoisobutyrate

600-00-0

methyl 2-bromo-2-methylpropanoate

23426-63-3

Methyl 2-Bromohexanoate

5445-19-2

Ethanol

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4-Methoxybenzoyl chloride

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γ-Butyrolactone

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(2-Bromoethyl)benzene

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Polyacrylic acid

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Carbomer

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Carbopol (8CI)

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Safe Shipment: 

 

We guarantee that your package will pass 100% through the US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

We have freight forwarders in these countries / regions, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

 

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What’s your MOQ?<span style="font-family: 'Times New Roman';color: rgb(102, 102, 102);letter-spacing: 0;fon

Allopregnanolone (ALLO), also known as 3α-hydroxy-5α-pregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of gamma-amininobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant activity.
Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).

Basic Info

Chemical Name

3α-hydroxy-5α-pregnan-20-one

Synonyms

(3α)-Allopregnanolone;Pregnan-20-one, 3-hydroxy-, (3α,5α)-;ALLOPREGNAN-3ALPHA-OL-20-ONE;3alpha-hydroxy-5alpha-pregnan-20-one;

CAS No.

516-54-1

Molecular Formula

C21H34O2

Molecular Weight

318.49300

PSA

37.30000

LogP

4.59520

 

Numbering system

UNII

S39XZ5QV8Y

Properties

Density

1.053g/cm3

Boiling Point

431.2ºC at 760mmHg

Flash Point

183.9ºC

Refractive Index

1.524

Storage Condition

Store at RT

Safety Info

Safety Statements

S22; S24/25

 

 

Company Introduction 

Wuhan Bosman Medicine Technology Co., Ltd. is a technological company with independent intellectual property rights, engaged in the development, production and operation of chemical products. Our company is a comprehensive enterprise integrating scientific and technological development and mass production. It is a factory specializing in the research and development and production of methylamine hydrochloride series products. The product quality is domestically leading. At the same time, we continue to explore and develop with the joint efforts of all employees of the company. The company has achieved rapid development, and its products are sold all over the world and are well received by customers. Our company has been responding to the call of the local government to speed up the adjustment of industrial structure and gradually expand production capacity. Currently, there are more than 600 employees in the factory and 29 technicians; among them, 11 are masters, 4 are PhDs, and 3 are MBAs. The annual planned production capacity of monomethylamine hydrochloride is more than 900 tons, the planned annual production capacity of dimethylamine hydrochloride is more than 500 tons, and the annual planned production capacity of trimethylamine hydrochloride is more than 700 tons. Products are exported to Southeast Asia, Europe, North America and South America. Our company's product quality is stable and reliable, and it has established friendly and stable business relationships with many well-known domestic and foreign companies. Our unit adheres to the principle of honest management, adheres to the tenet of quality assurance, and customer first, provides customers with products of outstanding quality and stable performance, and has won the unanimous recognition and favor of customers with efficient and perfect after-sales service. We look forward to working with colleagues and friends from all walks of life to create a new future.

 

Packaging  Details 

More items

 

4-methoxybenzoic acid

100-09-4

Xylazine hydrochloride

23076-35-9

Shikimic acid

138-59-0

5A-Hydroxy Laxogenin

56786-63-1

2-Bromo-4-Methylpropi

1451-83-8

2-phenylacetamide

103-81-1

lead diacetate trihydrate

6080-56-4

Arbidol

131707-25-0

phenacetn

62-44-2

lidocaine

137-58-6

benzocaine

1994/9/7

pregabalin

148553-50-8

Dimethocaine

94-15-5

Levamisole hcl

16595-80-5

Tetracaine hydrochloride

136-47-0

Btms

81646-13-1

Benzocaine Hydrochloride

23239-88-5

AIBN-64

78-67-1

methylamine hydrochloride

593-51-1

Tetracaine

94-24-6

lidocaine hydrochloride

73-78-9

SDIC

2893-78-9

4-Aminoacetophenone

99-92-3

2-Dimethylaminoisopropyl Chloride

4584-49-0

4-oxopiperidinium chloride

41979-39-9

α-Bromovalerophenone

49851-31-2



4-methylpropiophenone

5337-93-9

Phenyl-2-nitropropene

705-60-2

4-Fluorophenylacetone

459-03-0

4-Amino-3,5-dichlorophenacylbromide

37148-47-3

2-Bromo-1-phenyl-1-pentanone

49851-31-2

4-Amino-3,5-dichloroacetophenone

37148-48-4

Ethyl 2-Bromoisobutyrate

600-00-0

methyl 2-bromo-2-methylpropanoate

23426-63-3

Methyl 2-Bromohexanoate

5445-19-2

Ethanol

64-17-5

4-Methoxybenzoyl chloride

100-07-2

γ-Butyrolactone

96-48-0

(2-Bromoethyl)benzene

103-63-9

Polyacrylic acid

9003/1/4

Carbomer

9007-20-9

Carbopol (8CI)

54182-57-9



 

Safe Shipment: 

 

We guarantee that your package will pass 100% through the US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

We have freight forwarders in these countries / regions, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

 

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What’s your MOQ?<span style="font-family: 'Times New Roman';color: rgb(102, 102, 102);letter-spacing: 0;fon

Allopregnanolone (ALLO), also known as 3α-hydroxy-5α-pregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of gamma-amininobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant activity.
Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).

Basic Info

Chemical Name

3α-hydroxy-5α-pregnan-20-one

Synonyms

(3α)-Allopregnanolone;Pregnan-20-one, 3-hydroxy-, (3α,5α)-;ALLOPREGNAN-3ALPHA-OL-20-ONE;3alpha-hydroxy-5alpha-pregnan-20-one;

CAS No.

516-54-1

Molecular Formula

C21H34O2

Molecular Weight

318.49300

PSA

37.30000

LogP

4.59520

 

Numbering system

UNII

S39XZ5QV8Y

Properties

Density

1.053g/cm3

Boiling Point

431.2ºC at 760mmHg

Flash Point

183.9ºC

Refractive Index

1.524

Storage Condition

Store at RT

Safety Info

Safety Statements

S22; S24/25

 

 

Company Introduction 

Wuhan Bosman Medicine Technology Co., Ltd. is a technological company with independent intellectual property rights, engaged in the development, production and operation of chemical products. Our company is a comprehensive enterprise integrating scientific and technological development and mass production. It is a factory specializing in the research and development and production of methylamine hydrochloride series products. The product quality is domestically leading. At the same time, we continue to explore and develop with the joint efforts of all employees of the company. The company has achieved rapid development, and its products are sold all over the world and are well received by customers. Our company has been responding to the call of the local government to speed up the adjustment of industrial structure and gradually expand production capacity. Currently, there are more than 600 employees in the factory and 29 technicians; among them, 11 are masters, 4 are PhDs, and 3 are MBAs. The annual planned production capacity of monomethylamine hydrochloride is more than 900 tons, the planned annual production capacity of dimethylamine hydrochloride is more than 500 tons, and the annual planned production capacity of trimethylamine hydrochloride is more than 700 tons. Products are exported to Southeast Asia, Europe, North America and South America. Our company's product quality is stable and reliable, and it has established friendly and stable business relationships with many well-known domestic and foreign companies. Our unit adheres to the principle of honest management, adheres to the tenet of quality assurance, and customer first, provides customers with products of outstanding quality and stable performance, and has won the unanimous recognition and favor of customers with efficient and perfect after-sales service. We look forward to working with colleagues and friends from all walks of life to create a new future.

 

Packaging  Details 

More items

 

4-methoxybenzoic acid

100-09-4

Xylazine hydrochloride

23076-35-9

Shikimic acid

138-59-0

5A-Hydroxy Laxogenin

56786-63-1

2-Bromo-4-Methylpropi

1451-83-8

2-phenylacetamide

103-81-1

lead diacetate trihydrate

6080-56-4

Arbidol

131707-25-0

phenacetn

62-44-2

lidocaine

137-58-6

benzocaine

1994/9/7

pregabalin

148553-50-8

Dimethocaine

94-15-5

Levamisole hcl

16595-80-5

Tetracaine hydrochloride

136-47-0

Btms

81646-13-1

Benzocaine Hydrochloride

23239-88-5

AIBN-64

78-67-1

methylamine hydrochloride

593-51-1

Tetracaine

94-24-6

lidocaine hydrochloride

73-78-9

SDIC

2893-78-9

4-Aminoacetophenone

99-92-3

2-Dimethylaminoisopropyl Chloride

4584-49-0

4-oxopiperidinium chloride

41979-39-9

α-Bromovalerophenone

49851-31-2



4-methylpropiophenone

5337-93-9

Phenyl-2-nitropropene

705-60-2

4-Fluorophenylacetone

459-03-0

4-Amino-3,5-dichlorophenacylbromide

37148-47-3

2-Bromo-1-phenyl-1-pentanone

49851-31-2

4-Amino-3,5-dichloroacetophenone

37148-48-4

Ethyl 2-Bromoisobutyrate

600-00-0

methyl 2-bromo-2-methylpropanoate

23426-63-3

Methyl 2-Bromohexanoate

5445-19-2

Ethanol

64-17-5

4-Methoxybenzoyl chloride

100-07-2

γ-Butyrolactone

96-48-0

(2-Bromoethyl)benzene

103-63-9

Polyacrylic acid

9003/1/4

Carbomer

9007-20-9

Carbopol (8CI)

54182-57-9



 

Safe Shipment: 

 

We guarantee that your package will pass 100% through the US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

We have freight forwarders in these countries / regions, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

 

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What’s your MOQ?<span style="font-family: 'Times New Roman';color: rgb(102, 102, 102);letter-spacing: 0;fon