Allopregnanolone Pregnanalone CAS:516-54-1
Allopregnanolone (ALLO), also known as 3α-hydroxy-5α-pregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of gamma-amininobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant activity.
Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).
Basic Info
Chemical Name | 3α-hydroxy-5α-pregnan-20-one |
Synonyms | (3α)-Allopregnanolone;Pregnan-20-one, 3-hydroxy-, (3α,5α)-;ALLOPREGNAN-3ALPHA-OL-20-ONE;3alpha-hydroxy-5alpha-pregnan-20-one; |
CAS No. | 516-54-1 |
Molecular Formula | C21H34O2 |
Molecular Weight | 318.49300 |
PSA | 37.30000 |
LogP | 4.59520 |
Numbering system
UNII | S39XZ5QV8Y |
Properties
Density | 1.053g/cm3 |
Boiling Point | 431.2ºC at 760mmHg |
Flash Point | 183.9ºC |
Refractive Index | 1.524 |
Storage Condition | Store at RT |
Safety Info
Safety Statements | S22; S24/25 |
Company Introduction
Wuhan Bosman Medicine Technology Co., Ltd. is a technological company with independent intellectual property rights, engaged in the development, production and operation of chemical products. Our company is a comprehensive enterprise integrating scientific and technological development and mass production. It is a factory specializing in the research and development and production of methylamine hydrochloride series products. The product quality is domestically leading. At the same time, we continue to explore and develop with the joint efforts of all employees of the company. The company has achieved rapid development, and its products are sold all over the world and are well received by customers. Our company has been responding to the call of the local government to speed up the adjustment of industrial structure and gradually expand production capacity. Currently, there are more than 600 employees in the factory and 29 technicians; among them, 11 are masters, 4 are PhDs, and 3 are MBAs. The annual planned production capacity of monomethylamine hydrochloride is more than 900 tons, the planned annual production capacity of dimethylamine hydrochloride is more than 500 tons, and the annual planned production capacity of trimethylamine hydrochloride is more than 700 tons. Products are exported to Southeast Asia, Europe, North America and South America. Our company's product quality is stable and reliable, and it has established friendly and stable business relationships with many well-known domestic and foreign companies. Our unit adheres to the principle of honest management, adheres to the tenet of quality assurance, and customer first, provides customers with products of outstanding quality and stable performance, and has won the unanimous recognition and favor of customers with efficient and perfect after-sales service. We look forward to working with colleagues and friends from all walks of life to create a new future.
Packaging Details
More items
4-methoxybenzoic acid | 100-09-4 | Xylazine hydrochloride | 23076-35-9 |
Shikimic acid | 138-59-0 | 5A-Hydroxy Laxogenin | 56786-63-1 |
2-Bromo-4-Methylpropi | 1451-83-8 | 2-phenylacetamide | 103-81-1 |
lead diacetate trihydrate | 6080-56-4 | Arbidol | 131707-25-0 |
phenacetn | 62-44-2 | lidocaine | 137-58-6 |
benzocaine | 1994/9/7 | pregabalin | 148553-50-8 |
Dimethocaine | 94-15-5 | Levamisole hcl | 16595-80-5 |
Tetracaine hydrochloride | 136-47-0 | Btms | 81646-13-1 |
Benzocaine Hydrochloride | 23239-88-5 | AIBN-64 | 78-67-1 |
methylamine hydrochloride | 593-51-1 | Tetracaine | 94-24-6 |
lidocaine hydrochloride | 73-78-9 | SDIC | 2893-78-9 |
4-Aminoacetophenone | 99-92-3 | 2-Dimethylaminoisopropyl Chloride | 4584-49-0 |
4-oxopiperidinium chloride | 41979-39-9 | α-Bromovalerophenone | 49851-31-2 |
4-methylpropiophenone | 5337-93-9 | ||
Phenyl-2-nitropropene | 705-60-2 | 4-Fluorophenylacetone | 459-03-0 |
4-Amino-3,5-dichlorophenacylbromide | 37148-47-3 | 2-Bromo-1-phenyl-1-pentanone | 49851-31-2 |
4-Amino-3,5-dichloroacetophenone | 37148-48-4 | Ethyl 2-Bromoisobutyrate | 600-00-0 |
methyl 2-bromo-2-methylpropanoate | 23426-63-3 | Methyl 2-Bromohexanoate | 5445-19-2 |
Ethanol | 64-17-5 | 4-Methoxybenzoyl chloride | 100-07-2 |
γ-Butyrolactone | 96-48-0 | (2-Bromoethyl)benzene | 103-63-9 |
Polyacrylic acid | 9003/1/4 | Carbomer | 9007-20-9 |
Carbopol (8CI) | 54182-57-9 |
Safe Shipment:
We guarantee that your package will pass 100% through the US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.
We have freight forwarders in these countries / regions, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.
FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.
Q2:What’s your MOQ?<span style="font-family: 'Times New Roman';color: rgb(102, 102, 102);letter-spacing: 0;fon
Allopregnanolone (ALLO), also known as 3α-hydroxy-5α-pregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of gamma-amininobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant activity.
Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).
Basic Info
Chemical Name | 3α-hydroxy-5α-pregnan-20-one |
Synonyms | (3α)-Allopregnanolone;Pregnan-20-one, 3-hydroxy-, (3α,5α)-;ALLOPREGNAN-3ALPHA-OL-20-ONE;3alpha-hydroxy-5alpha-pregnan-20-one; |
CAS No. | 516-54-1 |
Molecular Formula | C21H34O2 |
Molecular Weight | 318.49300 |
PSA | 37.30000 |
LogP | 4.59520 |
Numbering system
UNII | S39XZ5QV8Y |
Properties
Density | 1.053g/cm3 |
Boiling Point | 431.2ºC at 760mmHg |
Flash Point | 183.9ºC |
Refractive Index | 1.524 |
Storage Condition | Store at RT |
Safety Info
Safety Statements | S22; S24/25 |
Company Introduction
Wuhan Bosman Medicine Technology Co., Ltd. is a technological company with independent intellectual property rights, engaged in the development, production and operation of chemical products. Our company is a comprehensive enterprise integrating scientific and technological development and mass production. It is a factory specializing in the research and development and production of methylamine hydrochloride series products. The product quality is domestically leading. At the same time, we continue to explore and develop with the joint efforts of all employees of the company. The company has achieved rapid development, and its products are sold all over the world and are well received by customers. Our company has been responding to the call of the local government to speed up the adjustment of industrial structure and gradually expand production capacity. Currently, there are more than 600 employees in the factory and 29 technicians; among them, 11 are masters, 4 are PhDs, and 3 are MBAs. The annual planned production capacity of monomethylamine hydrochloride is more than 900 tons, the planned annual production capacity of dimethylamine hydrochloride is more than 500 tons, and the annual planned production capacity of trimethylamine hydrochloride is more than 700 tons. Products are exported to Southeast Asia, Europe, North America and South America. Our company's product quality is stable and reliable, and it has established friendly and stable business relationships with many well-known domestic and foreign companies. Our unit adheres to the principle of honest management, adheres to the tenet of quality assurance, and customer first, provides customers with products of outstanding quality and stable performance, and has won the unanimous recognition and favor of customers with efficient and perfect after-sales service. We look forward to working with colleagues and friends from all walks of life to create a new future.
Packaging Details
More items
4-methoxybenzoic acid | 100-09-4 | Xylazine hydrochloride | 23076-35-9 |
Shikimic acid | 138-59-0 | 5A-Hydroxy Laxogenin | 56786-63-1 |
2-Bromo-4-Methylpropi | 1451-83-8 | 2-phenylacetamide | 103-81-1 |
lead diacetate trihydrate | 6080-56-4 | Arbidol | 131707-25-0 |
phenacetn | 62-44-2 | lidocaine | 137-58-6 |
benzocaine | 1994/9/7 | pregabalin | 148553-50-8 |
Dimethocaine | 94-15-5 | Levamisole hcl | 16595-80-5 |
Tetracaine hydrochloride | 136-47-0 | Btms | 81646-13-1 |
Benzocaine Hydrochloride | 23239-88-5 | AIBN-64 | 78-67-1 |
methylamine hydrochloride | 593-51-1 | Tetracaine | 94-24-6 |
lidocaine hydrochloride | 73-78-9 | SDIC | 2893-78-9 |
4-Aminoacetophenone | 99-92-3 | 2-Dimethylaminoisopropyl Chloride | 4584-49-0 |
4-oxopiperidinium chloride | 41979-39-9 | α-Bromovalerophenone | 49851-31-2 |
4-methylpropiophenone | 5337-93-9 | ||
Phenyl-2-nitropropene | 705-60-2 | 4-Fluorophenylacetone | 459-03-0 |
4-Amino-3,5-dichlorophenacylbromide | 37148-47-3 | 2-Bromo-1-phenyl-1-pentanone | 49851-31-2 |
4-Amino-3,5-dichloroacetophenone | 37148-48-4 | Ethyl 2-Bromoisobutyrate | 600-00-0 |
methyl 2-bromo-2-methylpropanoate | 23426-63-3 | Methyl 2-Bromohexanoate | 5445-19-2 |
Ethanol | 64-17-5 | 4-Methoxybenzoyl chloride | 100-07-2 |
γ-Butyrolactone | 96-48-0 | (2-Bromoethyl)benzene | 103-63-9 |
Polyacrylic acid | 9003/1/4 | Carbomer | 9007-20-9 |
Carbopol (8CI) | 54182-57-9 |
Safe Shipment:
We guarantee that your package will pass 100% through the US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.
We have freight forwarders in these countries / regions, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.
FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.
Q2:What’s your MOQ?<span style="font-family: 'Times New Roman';color: rgb(102, 102, 102);letter-spacing: 0;fon
Allopregnanolone (ALLO), also known as 3α-hydroxy-5α-pregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of gamma-amininobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant activity.
Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).
Basic Info
Chemical Name | 3α-hydroxy-5α-pregnan-20-one |
Synonyms | (3α)-Allopregnanolone;Pregnan-20-one, 3-hydroxy-, (3α,5α)-;ALLOPREGNAN-3ALPHA-OL-20-ONE;3alpha-hydroxy-5alpha-pregnan-20-one; |
CAS No. | 516-54-1 |
Molecular Formula | C21H34O2 |
Molecular Weight | 318.49300 |
PSA | 37.30000 |
LogP | 4.59520 |
Numbering system
UNII | S39XZ5QV8Y |
Properties
Density | 1.053g/cm3 |
Boiling Point | 431.2ºC at 760mmHg |
Flash Point | 183.9ºC |
Refractive Index | 1.524 |
Storage Condition | Store at RT |
Safety Info
Safety Statements | S22; S24/25 |
Company Introduction
Wuhan Bosman Medicine Technology Co., Ltd. is a technological company with independent intellectual property rights, engaged in the development, production and operation of chemical products. Our company is a comprehensive enterprise integrating scientific and technological development and mass production. It is a factory specializing in the research and development and production of methylamine hydrochloride series products. The product quality is domestically leading. At the same time, we continue to explore and develop with the joint efforts of all employees of the company. The company has achieved rapid development, and its products are sold all over the world and are well received by customers. Our company has been responding to the call of the local government to speed up the adjustment of industrial structure and gradually expand production capacity. Currently, there are more than 600 employees in the factory and 29 technicians; among them, 11 are masters, 4 are PhDs, and 3 are MBAs. The annual planned production capacity of monomethylamine hydrochloride is more than 900 tons, the planned annual production capacity of dimethylamine hydrochloride is more than 500 tons, and the annual planned production capacity of trimethylamine hydrochloride is more than 700 tons. Products are exported to Southeast Asia, Europe, North America and South America. Our company's product quality is stable and reliable, and it has established friendly and stable business relationships with many well-known domestic and foreign companies. Our unit adheres to the principle of honest management, adheres to the tenet of quality assurance, and customer first, provides customers with products of outstanding quality and stable performance, and has won the unanimous recognition and favor of customers with efficient and perfect after-sales service. We look forward to working with colleagues and friends from all walks of life to create a new future.
Packaging Details
More items
4-methoxybenzoic acid | 100-09-4 | Xylazine hydrochloride | 23076-35-9 |
Shikimic acid | 138-59-0 | 5A-Hydroxy Laxogenin | 56786-63-1 |
2-Bromo-4-Methylpropi | 1451-83-8 | 2-phenylacetamide | 103-81-1 |
lead diacetate trihydrate | 6080-56-4 | Arbidol | 131707-25-0 |
phenacetn | 62-44-2 | lidocaine | 137-58-6 |
benzocaine | 1994/9/7 | pregabalin | 148553-50-8 |
Dimethocaine | 94-15-5 | Levamisole hcl | 16595-80-5 |
Tetracaine hydrochloride | 136-47-0 | Btms | 81646-13-1 |
Benzocaine Hydrochloride | 23239-88-5 | AIBN-64 | 78-67-1 |
methylamine hydrochloride | 593-51-1 | Tetracaine | 94-24-6 |
lidocaine hydrochloride | 73-78-9 | SDIC | 2893-78-9 |
4-Aminoacetophenone | 99-92-3 | 2-Dimethylaminoisopropyl Chloride | 4584-49-0 |
4-oxopiperidinium chloride | 41979-39-9 | α-Bromovalerophenone | 49851-31-2 |
4-methylpropiophenone | 5337-93-9 | ||
Phenyl-2-nitropropene | 705-60-2 | 4-Fluorophenylacetone | 459-03-0 |
4-Amino-3,5-dichlorophenacylbromide | 37148-47-3 | 2-Bromo-1-phenyl-1-pentanone | 49851-31-2 |
4-Amino-3,5-dichloroacetophenone | 37148-48-4 | Ethyl 2-Bromoisobutyrate | 600-00-0 |
methyl 2-bromo-2-methylpropanoate | 23426-63-3 | Methyl 2-Bromohexanoate | 5445-19-2 |
Ethanol | 64-17-5 | 4-Methoxybenzoyl chloride | 100-07-2 |
γ-Butyrolactone | 96-48-0 | (2-Bromoethyl)benzene | 103-63-9 |
Polyacrylic acid | 9003/1/4 | Carbomer | 9007-20-9 |
Carbopol (8CI) | 54182-57-9 |
Safe Shipment:
We guarantee that your package will pass 100% through the US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.
We have freight forwarders in these countries / regions, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.
FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.
Q2:What’s your MOQ?<span style="font-family: 'Times New Roman';color: rgb(102, 102, 102);letter-spacing: 0;fon
